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A Novel Technology to Illuminate Drug:Target Interactions in Living Cells

NanoBRET™ technology allows scientists to quantify protein:protein and protein:ligand interactions with a precision and sensitivity never possible before. 

Here, Dr. Gary Allenby, Chief Scientific Officer at Aurelia Bioscience Ltd., describes use of NanoBRET in live-cell compound screening assays for kinase target engagement. 

NanoBRET is also being used to expedite analysis of protein degraders during drug development. Check out the talk below from Promega's Jim Vasta to learn more.

Studying PROTAC-Mediated Protein Degradation

We are very happy to have implemented the large volume extraction kits in our analysis of wastewater for SARS-CoV-2. The integration of concentration and extraction steps has been instrumental in expediting our workflow. The kits also provide higher reproducibility between biological replicates compared to the method we were using previously. 

Jeseth Delgado Vela, Howard University.

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